Subject. This article discusses the organizational and economic processes, and conditions for the formation and development of inter-regional clusters. Objectives. The article aims to clarify ideas and develop recommendations to assess the conditions and possibilities of inter-regional cluster forming. Methods. For the study, we used statistical analysis, graphical, and expert assessment methods, and a literature review. Results. The article proposes certain phases and an algorithm to form inter-regional clusters as potential economic growth zones of the regions. Conclusions and Relevance. The inter-regional cluster formation and development should be based on the economic-growth-zone theory and models based on the principles of inclusive development and smart specialization. The results of the study may be a basis to develop a strategy for inter-regional clusters operating at the level of the country's macro-regions.
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