Subject. This article deals with the issues of economic security of the monocity and the region, focusing on determining an algorithm of these population areas' interrelation and interdependence. Objectives. The article aims to study the economic security of the monocity and the region within the framework of algorithmization, necessitating the need to design an inter-territorial system of communications, which would ensure interaction between the monocity and the region from the position of economic security of the Russian Federation. Methods. For the study, I used the methods of theoretical grounds, conceptual differentiation, structuring, grouping, modeling, algorithm presentation, and others. Results. The article presents a developed algorithm of interrelation and interdependence of monocities and the region (the subject) from the position of economic security of the Russian Federation. Conclusions. Transforming the process environment makes it necessary to focus on developing algorithms that help conduct research on several territorial objects at a time.
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