Importance The article comprehensively examines the regional aspect of the process of NBIC-convergence, i.e. the integration of nanotechnology, biotechnology, information technology and cognitive science, and their combinatorial forms. Objectives The purpose of the article is a pithy multidimensional analysis of the causes and forms of asymmetry and asynchrony of NBIC-convergence in the regions of Russia, as well as improving the methodological foundations of assessment of the adaptive capacity of regions to this technological shift. Methods The article relies on a combination of systems, evolutionary, institutional, comparative, and descriptive analyses. Results The analysis reveals that NBIC-convergence in regions of the Russian Federation is developing asynchronously, asymmetrically and in distorted forms. There are significant interregional disparities in capacity and dynamics of the development of nanotechnology, high regional heterogeneity of the nanotechnology network; regional components of strategic management of bioindustry are not developed; the digital divide of the RF subjects still remains; different NBIC-industries are apparently developing at different rates; some territorial innovation clusters in the field of NBIC-convergence are the only evidence. Conclusions Lack of development of methodological bases of assessment of the adaptive capacity of regional innovation systems to NBIC-convergence process has stimulated the development of our own method. Testing of this technique in the Southern Federal District regions made it possible to quantitatively justify the conclusion about the extremely high differentiation of the innovation potential of subjects of the Russian Federation in the segment of the most prospective general-purpose technologies.
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